GZMB anticorps (AA 7-227)

N° du produit ABIN126926

L’anticorps Souris Monoclonal anti-GZMB a été validé pour WB, FACS, IP, IHC (p) et IHC (fro). Il convient pour détecter GZMB dans des échantillons de Humain.

Aperçu rapide pour GZMB anticorps (AA 7-227) (ABIN126926)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: B18-1

Détail du produit anti-GZMB anticorps

Épitope: AA 7-227

Specificité: Detects human Granzyme B.

Attributs du produit: Synonyms: Granzyme-2, CGL1, CTSGL1, CSPB, CTLA1, CTLA-1, GRB, SECT, Fragmentin-2, T-cell serineprotease 1-3E, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Cathepsin G-like1

Purification: Affinity Purified

Immunogène: Human recombinant granzyme B (aa 7-227)

Isotype: IgG1

Information d'application

Indications d'application: Western Blot. Immunoprecipitation. Flow Cytometry. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS containing 1 mg/mL BSA, 1.5 mM Sodium Azide and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C to -70 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Sujet: Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

ID gène: 3002

UniProt: P10144

Pathways: Apoptose, Caspase Cascade in Apoptosis